GLP-1 weight loss under a doctor's care
Semaglutide and tirzepatide can help people with obesity lose weight. They are prescription medicines that need the right person, safety checks, slow dose increases and a plan to protect muscle and keep the weight off.
Dwarka Sector 6 clinic & online across India · Prescribed only after a medical assessment
Who it may suit
BMI 30 or more
Obesity, after diet and activity changes alone have not been enough.
BMI 27 or more with a health problem
For example type 2 diabetes, prediabetes, high BP, fatty liver, high cholesterol or sleep apnoea. Asian adults often face these risks at lower BMIs.
Type 2 diabetes with excess weight
GLP-1 medicines lower blood sugar and weight together, and some protect the heart.
Not suitable for
Pregnancy or planning pregnancy, breastfeeding, a personal or family history of medullary thyroid cancer or MEN2, and some people with past pancreatitis.
Not a quick fix
These medicines are not for a few kilos before an event. They work best as part of long-term treatment.
Decided after assessment
Whether a GLP-1 medicine is right for you, and which one, is decided only after your history, examination and tests.
How supervised GLP-1 treatment works
Weight usually comes back if the medicine is stopped without a plan. That is why we prepare for the long term from the first visit.
Medical assessment first
Weight history, medicines, BMI, waist, BP, and tests such as HbA1c, kidney and liver function, lipids and thyroid. We also look for causes of weight gain.
Start low, increase slowly
The dose goes up step by step over weeks to limit nausea. You'll learn how to inject or take the medicine and what to do on a bad day.
Protect muscle
Enough protein at each meal and strength exercise 2–3 times a week, so the weight lost is mostly fat, not muscle.
Monthly follow-up
Weight, waist, side effects, sugar and BP are reviewed, in clinic or online. The plan includes what happens when the medicine is reduced or stopped.
Frequently asked questions
How much weight can I lose with semaglutide or tirzepatide?
In large studies, people lost on average about 15% of body weight with semaglutide 2.4 mg and around 20% with the highest tirzepatide doses over roughly 16–18 months, together with diet and activity changes. Individual results vary.
What are the common side effects?
Nausea, fullness, constipation, diarrhoea and reflux, mostly when starting or increasing the dose. Rarer problems include gallstones and pancreatitis, which is why follow-up matters. Severe stomach pain needs urgent care.
Will the weight come back if I stop?
Often, yes, if the medicine is stopped suddenly with no lifestyle plan. Gradual dose reduction, protein, strength training and regular review help keep weight off.
Can I buy these medicines without a prescription?
No, and you shouldn't. They are prescription medicines, and fake or unregulated versions sold online can be dangerous. Use only medicines prescribed by your doctor and supplied by a licensed pharmacy.
Is GLP-1 treatment available through online consultation?
Follow-up can be online. The first assessment is best in person at the Dwarka clinic, or online with recent test reports and accurate weight, waist and BP readings.
Do I still need to diet?
You will eat less because appetite falls. The focus is on eating well, not starving: enough protein, vegetables, fibre and fluids, so you feel well and keep muscle.
Read more from Dr. Pankaj Kumar
Tirzepatide vs semaglutide: what patients should understandSemaglutide side effects and how to manage themHow to avoid muscle loss during weight lossWhy weight comes back after dietingSee a doctor in Dwarka Sector 6
Doctors Lane, Pocket 2, Sector 6, Dwarka, New Delhi · Mon–Sat 10 AM–2 PM & 5–9 PM · Sun 10 AM–2 PM
This page gives general information and is not a substitute for a consultation. Treatment is decided after examination and tests. Last reviewed by Dr. Pankaj Kumar, MBBS, DNB (Family Medicine), on 21 October 2026.